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α-SMA Polyclonal Antibody, 100μg, (ATB-T5120)

$199.00
In stock
Product Details

Background: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]Product datasheet: Overview Product Description α-SMA Polyclonal Antibody, 100μg, (ATB-T5120) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human α-SMA. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: α-Smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study. Sinn M, et al. Br J Cancer, 2014 Nov 11. PMID 25314063 Twins with progressive thoracic aortic aneurysm, recurrent dissection and ACTA2 mutation. Ware SM, et al. Pediatrics, 2014 Oct. PMID 25225139 ACTA2 is not a major genetic risk gene for Chinese patients with moyamoya disease. Hu FY, et al. Int J Stroke, 2013 Oct. PMID 24024919 Alpha-smooth muscle actin (ACTA2) is required for metastatic potential of human lung adenocarcinoma. Lee HW, et al. Clin Cancer Res, 2013 Nov 1. PMID 23995859 Prevalence of infarct and villous clumps, and the expression of α-smooth muscle actin in the placental basal plate in severe preeclampsia. Kong M, et al. Mol Med Rep, 2013 Oct. PMID 23982059

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α-SMA Polyclonal Antibody, 100μg, (ATB-T5120)
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