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A Cyclase IX Polyclonal Antibody, 100μg, (ATB-T0031)

$199.00
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Background: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description A Cyclase IX Polyclonal Antibody, 100μg, (ATB-T0031) Image Species Reactivities Human Immunogen Synthesized peptide derived from the N-terminal region of human A Cyclase IX. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Coordinate down-regulation of adenylyl cyclase isoforms and the stimulatory G protein (G(s)) in intestinal epithelial cell differentiation. Choi LJ, et al. J Biol Chem, 2010 Apr 23. PMID 20157112 Free PMC Article Rubinstein-Taybi syndrome associated with Chiari type I malformation caused by a large 16p13.3 microdeletion: a contiguous gene syndrome? Wójcik C, et al. Am J Med Genet A, 2010 Feb. PMID 20101707 Novel regulatory properties of human type 9 adenylate cyclase. Cumbay MG, et al. J Pharmacol Exp Ther, 2004 Jul. PMID 14996950 An Ile to Met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced beta2-adrenergic receptor stimulation. Small KM, et al. Pharmacogenetics, 2003 Sep. PMID 12972952 Association analysis of adenylate cyclase type 9 gene using pedigree disequilibrium test in bipolar disorder. Toyota T, et al. Mol Psychiatry, 2002. PMID 12082561

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A Cyclase IX Polyclonal Antibody, 100μg, (ATB-T0031)
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