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ACSVL6 Polyclonal Antibody, 100μg, (ATB-T0095)

$199.00
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Background: The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description ACSVL6 Polyclonal Antibody, 100μg, (ATB-T0095) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human ACSVL6. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. Setchell KD, et al. Gastroenterology, 2013 May. PMID 23415802 Free PMC Article Bile acid-CoA ligase deficiency--a new inborn error of bile acid metabolism. Chong CP, et al. J Inherit Metab Dis, 2012 May. PMID 22089923 A promoter polymorphism in the liver-specific fatty acid transport protein 5 is associated with features of the metabolic syndrome and steatosis. Auinger A, et al. Horm Metab Res, 2010 Nov. PMID 20945272 The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase. Steinberg SJ, et al. J Biol Chem, 2000 May 26. PMID 10749848 Heat shock transcription factor (Hsf)-4b recruits Brg1 during the G1 phase of the cell cycle and regulates the expression of heat shock proteins. Tu N, et al. J Cell Biochem, 2006 Aug 15. PMID 16552721

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ACSVL6 Polyclonal Antibody, 100μg, (ATB-T0095)
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