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ACYP2 Polyclonal Antibody, 100μg, (ATB-T0109)

$199.00
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Background: Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description ACYP2 Polyclonal Antibody, 100μg, (ATB-T0109) Image Species Reactivities Human,Rat Immunogen Synthesized peptide derived from the Internal region of human ACYP2. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Stabilization of a protein conferred by an increase in folded state entropy. Dagan S, et al. Proc Natl Acad Sci U S A, 2013 Jun 25. PMID 23754389 Free PMC Article Rapid oligomer formation of human muscle acylphosphatase induced by heparan sulfate. Motamedi-Shad N, et al. Nat Struct Mol Biol, 2012 Apr 22. PMID 22522822 Mutational analysis of the aggregation-prone and disaggregation-prone regions of acylphosphatase. Calamai M, et al. J Mol Biol, 2009 Apr 10. PMID 18809411 Glycine residues appear to be evolutionarily conserved for their ability to inhibit aggregation. Parrini C, et al. Structure, 2005 Aug. PMID 16084386 Reversal of protein aggregation provides evidence for multiple aggregated States. Calamai M, et al. J Mol Biol, 2005 Feb 18. PMID 15670608

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ACYP2 Polyclonal Antibody, 100μg, (ATB-T0109)
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