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ASIC3 Polyclonal Antibody, 100μg, (ATB-T15200)
Background: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]Product datasheet: Overview Product Description ASIC3 Polyclonal Antibody, 100μg, (ATB-T15200) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human ASIC3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Lignan from thyme possesses inhibitory effect on ASIC3 channel current. Dubinnyi MA, et al. J Biol Chem, 2012 Sep 21. PMID 22854960 Free PMC Article Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions. Delaunay A, et al. Proc Natl Acad Sci U S A, 2012 Aug 7. PMID 22829666 Free PMC Article ASIC3 channels in multimodal sensory perception. Li WG, et al. ACS Chem Neurosci, 2011 Jan 19. PMID 22778854 Free PMC Article Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels. Yu Y, et al. J Biol Chem, 2011 Jul 15. PMID 21586569 Free PMC Article Association between an ASIC3 gene variant and insulin resistance in Taiwanese. Wu S, et al. Clin Chim Acta, 2010 Aug 5. PMID 20416288
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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