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AbinScience InVivoMAb Anti-HCMV/HHV-5 gB Neutralizing Antibody (1G2) (VK665030-50UG)
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AbinScience InVivoMAb Anti-HCMV/HHV-5 gB Neutralizing Antibody (1G2) (VK665030-50UG)

Store / Antibodies and Immunodetection Reagents
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Product Details

Overview

Catalog No. VK665030-50UG
Description
AbinScience InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)[1G2] (VK665030-50UG) is a human monoclonal antibody detecting Envelope glycoprotein B in ELISA, Neutralization.
Species reactivity Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5)
Applications ELISA, Neutralization
Host species Human
Isotype IgG1, kappa
Clone ID 1G2
Clonality Monoclonal
Target Envelope glycoprotein B, gB, gB, UL55
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P13201
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Note For research use only. Not suitable for clinical or therapeutic use.

Images


SDS-PAGE for InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)

Detects recombinant HCMV/HHV5 Envelope glycoprotein B/gB (Catalog No: VK665011) in indirect ELISA


Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.

Lane 1: recombinant HCMV/HHV5 Envelope glycoprotein B/gB(Catalog No: VK665011)

Lane 2: negative control

Lane 3: negative control

Datasheets

InVivoMAb Anti-HCMV/HHV-5 gB Neutralizing Antibody (1G2).pdf



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AbinScience InVivoMAb Anti-HCMV/HHV-5 gB Neutralizing Antibody (1G2) (VK665030-50UG)
Store / Antibodies and Immunodetection Reagents
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