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AbinScience InVivoMAb Anti-RSV G/Major surface glycoprotein G Antibody (3G12) (VK562030-50UG)
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AbinScience InVivoMAb Anti-RSV G/Major surface glycoprotein G Antibody (3G12) (VK562030-50UG)

Store / Antibodies and Immunodetection Reagents / Primary Antibodies / InVivoMAb
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Product Details

Overview

Catalog No. VK562030-50UG
Description
AbinScience InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12)[3G12] (VK562030-50UG) is a human monoclonal antibody detecting Major surface glycoprotein G in ELISA, Neutralization, WB.
HIGHLIGHTS
  • ● Multi-Application — Validated across multiple applications.
Species reactivity Human respiratory syncytial virus A (strain A2)
Applications ELISA, Neutralization, WB
Host species Human
Isotype IgG1, kappa
Clone ID 3G12
Clonality Monoclonal
Target Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, Mature secreted glycoprotein G, Mature sG, G
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P03423
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Major surface glycoprotein G is a ~32 kDa protein. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable).

1. Feldman, SA. et al. (1999) Journal of virology 73, 6610-7. PMID: 10400758
2. Feldman, SA. et al. (2000) Journal of virology 74, 6442-7. PMID: 10864656
3. Levine, S. et al. (1987) The Journal of general virology 68 ( Pt 9), 2521-4. PMID: 3655746
4. Tripp, RA. et al. (2001) Nature immunology 2, 732-8. PMID: 11477410
5. Jeong, KI. et al. (2015) PloS one 10, e0130517. PMID: 26107373
6. Johnson, SM. et al. (2015) PLoS pathogens 11, e1005318. PMID: 26658574
Note For research use only. Not suitable for clinical or therapeutic use.

Images


SDS-PAGE for InVivoMAb Anti-HRSV G/Major surface glycoprotein G Antibody (3G12)

Detects recombinant HRSV G/Major surface glycoprotein G (Catalog No: VK562011) in indirect ELISA

Datasheets

InVivoMAb Anti-RSV G/Major surface glycoprotein G Antibody (3G12).pdf


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AbinScience InVivoMAb Anti-RSV G/Major surface glycoprotein G Antibody (3G12) (VK562030-50UG)
Store / Antibodies and Immunodetection Reagents / Primary Antibodies / InVivoMAb
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