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AbinScience InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) (VK805010-100UG)

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Product Details

Overview

Catalog No. VK805010-100UG
Description
AbinScience InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009)[CR3009] (VK805010-100UG) is a human monoclonal antibody detecting Nucleoprotein in ELISA, FCM, IF, Neutralization. Suitable for SARS-CoV-2.
HIGHLIGHTS
  • Multi-Application — Validated across multiple applications.
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivity SARS-CoV-2
Applications ELISA, FCM, IF, Neutralization
Host species Human
Isotype IgG1, kappa
Clone ID CR3009
Clonality Monoclonal
Target Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N Protein, SARS-CoV-2
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P0DTC9
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Nucleoprotein (NP) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions.

1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373
2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782
3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661
Note For research use only. Not suitable for clinical or therapeutic use.

Images


Western blot analysis was performed using anti-nucleoprotein monoclonal antibody at 1ug/mL on various samples.

Lane 1: recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011)

Lane 2: negative control

Detects recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011) in indirect ELISA

Datasheets

InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009).pdf

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AbinScience InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) (VK805010-100UG)
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