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Abinscience InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191) (HV033010-100ug)
Overview
| Catalog No. | HV033010-100ug |
|---|---|
| Description | Abinscience InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191)[Iv0191] (HV033010-100ug) is a human monoclonal
antibody detecting High-temperature requirement A serine peptidase 1
in Blocking, ELISA. Suitable for Human.
|
| Species reactivity | Human |
| Applications | Blocking, ELISA |
| Host species | Human |
| Isotype | IgG2, kappa |
| Clone ID | Iv0191 |
| Clonality | Monoclonal |
| Target | High-temperature requirement A serine peptidase 1, Serine protease 11, HTRA1, PRSS11, HTRA, Serine protease HTRA1, L56 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q92743 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Serine protease HTRA1 (PRSS11) is a ~51 kDa protein. Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Images
SDS-PAGE for InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191).