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Abinscience InVivoMAb Anti-Human PAUF/ZG16B Antibody (Iv0188) (HB774010-1mg)

Abinscience InVivoMAb Anti-Human PAUF/ZG16B Antibody (Iv0188) (HB774010-1mg)

Store / Antibodies and Immunodetection Reagents / Primary Antibodies / InVivoMAb
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Product Details

Overview

Catalog No. HB774010-1mg
Description
Abinscience InVivoMAb Anti-Human PAUF Antibody (Iv0188)[Iv0188] (HB774010-1mg) is a human monoclonal antibody detecting Pancreatic adenocarcinoma upregulated factor in Blocking, ELISA. Suitable for Human.
Species reactivity Human
Applications Blocking, ELISA
Host species Human
Isotype IgG1, kappa
Clone ID Iv0188
Clonality Monoclonal
Target Pancreatic adenocarcinoma upregulated factor, PAUF
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q96DA0
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Pancreatic adenocarcinoma up-regulated factor (PAUF) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway.

1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558
2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292
3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715
Note For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE for InVivoMAb Anti-Human PAUF Antibody (Iv0188)

Datasheets

InVivoMAb Anti-Human PAUF/ZG16B Antibody (Iv0188).pdf

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Abinscience InVivoMAb Anti-Human PAUF/ZG16B Antibody (Iv0188) (HB774010-1mg)
Store / Antibodies and Immunodetection Reagents / Primary Antibodies / InVivoMAb
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