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Anti-ATM (Q2442P) Mouse Monoclonal Antibody, 100 µl (26142)

$495.00
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Background Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers. Tested Applications ELISA, WB, IHC Source Species Mouse Species Reactivity Recognizes ATM(Q2442P), but not wild type ATM protein from vertebrates. Datasheet Western Blot Western blot analysis of recombinant ATM (Q2442P) and wildtype proteins. Purified His-tagged ATM (Q2442P) protein (amino acids 1-76, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-ATM (Q2442P) mouse monoclonal antibody (Cat. #NEBA10174).

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Anti-ATM (Q2442P) Mouse Monoclonal Antibody, 100 µl (26142)