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BNIP-3 Polyclonal Antibody, 100μg, (ATB-T15154)

$199.00
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Background: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014]Product datasheet: Overview Product Description BNIP-3 Polyclonal Antibody, 100μg, (ATB-T15154) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human BNIP-3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: BNIP3 regulates AT101 [(-)-gossypol] induced death in malignant peripheral nerve sheath tumor cells. Kaza N, et al. PLoS One, 2014. PMID 24824755 Free PMC Article The interplay between epigenetic silencing, oncogenic KRas and HIF-1 regulatory pathways in control of BNIP3 expression in human colorectal cancer cells. Swiderek E, et al. Biochem Biophys Res Commun, 2013 Nov 29. PMID 24211581 [Autophagy and BNIP3 protein in tumorogenesis]. Swiderek E, et al. Postepy Hig Med Dosw (Online), 2013 May 9. PMID 23667095 Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death. Ma X, et al. Autophagy, 2012 Mar. PMID 22302006 Free PMC Article Genome-wide CpG island profiling of intraductal papillary mucinous neoplasms of the pancreas. Hong SM, et al. Clin Cancer Res, 2012 Feb 1. PMID 22173550 Free PMC Article

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BNIP-3 Polyclonal Antibody, 100μg, (ATB-T15154)
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