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BRS-3 Polyclonal Antibody, 100μg, (ATB-T0534)

$199.00
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Product Details

Background: The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]Product datasheet: Overview Product Description BRS-3 Polyclonal Antibody, 100μg, (ATB-T0534) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human BRS-3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Human BRS-3 receptor: functions/role in cell signaling pathways and glucose metabolism in obese or diabetic myocytes. Ramos-Álvarez I, et al. Peptides, 2014 Jan. PMID 24220502 Bombesin receptor subtype-3 (BRS-3), a novel candidate as therapeutic molecular target in obesity and diabetes. Ramos-Álvarez I, et al. Mol Cell Endocrinol, 2013 Mar 10. PMID 23291341 Activation of bombesin receptor subtype-3 stimulates adhesion of lung cancer cells. Hou X, et al. Lung Cancer, 2006 Nov. PMID 16979789 Ability of various bombesin receptor agonists and antagonists to alter intracellular signaling of the human orphan receptor BRS-3. Ryan RR, et al. J Biol Chem, 1998 May 29. PMID 9593699 BRS-3: a novel bombesin receptor subtype selectively expressed in testis and lung carcinoma cells. Fathi Z, et al. J Biol Chem, 1993 Mar 15. PMID 8383682

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BRS-3 Polyclonal Antibody, 100μg, (ATB-T0534)
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