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BTF Polyclonal Antibody, 100μg, (ATB-T0542)

$199.00
In stock
Product Details

Background: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description BTF Polyclonal Antibody, 100μg, (ATB-T0542) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human BTF. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair. Lee YY, et al. Cell Death Dis, 2012 Jul 26. PMID 22833098 Free PMC Article BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection. Lee SH, et al. Proc Natl Acad Sci U S A, 2012 Jun 12. PMID 22645331 Free PMC Article In search of a function for BCLAF1. Sarras H, et al. ScientificWorldJournal, 2010 Jul 20. PMID 20661537 The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells. Rénert AF, et al. J Proteome Res, 2009 Oct. PMID 19705920 Bcl-2-associated transcription factor 1 interacts with fragile X-related protein 1. Ma Y, et al. Acta Biochim Biophys Sin (Shanghai), 2014 Feb. PMID 24389646

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BTF Polyclonal Antibody, 100μg, (ATB-T0542)
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