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Brk Polyclonal Antibody, 100μg, (ATB-T0525)
Background: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]Product datasheet: Overview Product Description Brk Polyclonal Antibody, 100μg, (ATB-T0525) Species Reactivities Human Immunogen Synthesized peptide derived from human Brk around the non-phosphorylation site of Y447. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: PTK6 promotes cancer migration and invasion in pancreatic cancer cells dependent on ERK signaling. Ono H, et al. PLoS One, 2014. PMID 24788754 Free PMC Article Protein tyrosine kinase 6 is associated with nasopharyngeal carcinoma poor prognosis and metastasis. Liu LN, et al. J Transl Med, 2013 Jun 9. PMID 23758975 Free PMC Article Low expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma. Liu XK, et al. J Transl Med, 2013 Mar 7. PMID 23497344 Free PMC Article Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage. Gierut JJ, et al. Mol Cancer Ther, 2012 Nov. PMID 22989419 Free PMC Article Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma. Ma S, et al. Gastroenterology, 2012 Sep. PMID 22705009
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Why is IntelixBio LLC so popular?
IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
Visit our online shop to view our available medical lab equipment and purchase the items that match your unique styles and needs today.
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Where do you ship your medical lab equipment?
We ship our medical lab equipment to customers nationwide. Browse our online shop to view our impressive inventory of available lab equipment today and purchase the products that meet your unique style and needs. We can't wait to prove why Intelixbio.com is one of the nation's best medical lab supply providers.
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How can I contact your company?
You can reach IntelixBio LLC by phone at 240-316-3161, by email at info@intelixbio.com, or by filling out one of the contact forms on our website.
When you contact our team, you can expect fast, friendly, and professional assistance with all your medical lab equipment needs.