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CA IV Polyclonal Antibody, 100μg, (ATB-T5128)

$199.00
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Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description CA IV Polyclonal Antibody, 100μg, (ATB-T5128) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human CA IV. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Membrane associated carbonic anhydrase IV (CA IV): a personal and historical perspective. Waheed A, et al. Subcell Biochem, 2014. PMID 24146379 Carbonic anhydrase VI exon 2 genetic polymorphism in Turkish subjects with low caries experience (preliminary study). Yarat A, et al. In Vivo, 2011 Nov-Dec. PMID 22021688 Cell-specific differences in the processing of the R14W CAIV mutant associated with retinitis pigmentosa 17. Pandor A, et al. J Cell Biochem, 2010 Oct 15. PMID 20626030 Screening for the carbonic anhydrase IV gene mutations in Chinese retinitis pigmentosa patients. Tian Y, et al. Curr Eye Res, 2010 May. PMID 20450258 Pathogenesis of retinitis pigmentosa associated with apoptosis-inducing mutations in carbonic anhydrase IV. Datta R, et al. Proc Natl Acad Sci U S A, 2009 Mar 3. PMID 19211803 Free PMC Article

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CA IV Polyclonal Antibody, 100μg, (ATB-T5128)
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