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CARD 6 Polyclonal Antibody, 100μg, (ATB-T0637)

$199.00
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Product Details

Background: This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description CARD 6 Polyclonal Antibody, 100μg, (ATB-T0637) Image Species Reactivities Human Immunogen Synthesized peptide derived from the N-terminal region of human CARD 6. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Expression of CARD6, an NF-kappaB activator, in gastric, colorectal and oesophageal cancers. Kim SS, et al. Pathology, 2010 Jan. PMID 20025480 CARD tricks: controlling the interactions of CARD6 with RICK and microtubules. Dufner A, et al. Cell Cycle, 2006 Apr. PMID 16582588 Caspase recruitment domain protein 6 is a microtubule-interacting protein that positively modulates NF-kappaB activation. Dufner A, et al. Proc Natl Acad Sci U S A, 2006 Jan 24. PMID 16418290 Free PMC Article CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways. Stehlik C, et al. J Biol Chem, 2003 Aug 22. PMID 12775719 Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983

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CARD 6 Polyclonal Antibody, 100μg, (ATB-T0637)
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