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CD163b Polyclonal Antibody, 100μg, (ATB-T15406)

$199.00
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Background: This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]Product datasheet: Overview Product Description CD163b Polyclonal Antibody, 100μg, (ATB-T15406) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human CD163b. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Antagonistic regulation of macrophage phenotype by M-CSF and GM-CSF: implication in atherosclerosis. Brochériou I, et al. Atherosclerosis, 2011 Feb. PMID 21159337 Identification of the CD163 protein domains involved in infection of the porcine reproductive and respiratory syndrome virus. Van Gorp H, et al. J Virol, 2010 Mar. PMID 20032174 Free PMC Article Cloning of a novel scavenger receptor cysteine-rich type I transmembrane molecule (M160) expressed by human macrophages. Gronlund J, et al. J Immunol, 2000 Dec 1. PMID 11086079 Assignment of CD163B, the gene encoding M160, a novel scavenger receptor, to human chromosome 12p13.3 by in situ hybridization and somatic cell hybrid analysis. Stover CM, et al. Cytogenet Cell Genet, 2000. PMID 11124526 Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1. Denner J, et al. PLoS One, 2013. PMID 23383108 Free PMC Article

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CD163b Polyclonal Antibody, 100μg, (ATB-T15406)
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