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CD32 Polyclonal Antibody, 100μg, (ATB-T0754)

$199.00
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Background: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]Product datasheet: Overview Product Description CD32 Polyclonal Antibody, 100μg, (ATB-T0754) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human CD32 around the non-phosphorylation site of Y292. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages. Nagelkerke SQ, et al. Blood, 2014 Dec 11. PMID 25352126 Defunctioning polymorphism in the immunoglobulin G inhibitory receptor (FcγRIIB-T/T232) does not impact on kidney transplant or recipient survival. Clatworthy MR, et al. Transplantation, 2014 Aug 15. PMID 25022320 Free PMC Article [Preparation of lentivirus containing human FcγRIIB gene and FcγRIIB expression in HT-1080 cells]. Liu H, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2014 Jun. PMID 24909272 Cell contact-dependent priming and Fc interaction with CD32+ immune cells contribute to the TGN1412-triggered cytokine response. Bartholomaeus P, et al. J Immunol, 2014 Mar 1. PMID 24470499 [Decreased FcγRIIb1 translocation to lipid raft signaling domains in activated B lymphocytes from patients with systemic lupus erythematosus]. Peng K, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2014 Jan. PMID 24405601

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CD32 Polyclonal Antibody, 100μg, (ATB-T0754)
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