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CEP350 Polyclonal Antibody, 100μg, (ATB-T0860)

$199.00
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Product Details

Background: The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description CEP350 Polyclonal Antibody, 100μg, (ATB-T0860) Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human CEP350. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex. Hoppeler-Lebel A, et al. J Cell Sci, 2007 Sep 15. PMID 17878239 A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Yan X, et al. Mol Biol Cell, 2006 Feb. PMID 16314388 Free PMC Article The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells. Eguether T, et al. Nat Commun, 2014 Aug 19. PMID 25134987 The Arabidopsis TRM1-TON1 interaction reveals a recruitment network common to plant cortical microtubule arrays and eukaryotic centrosomes. Drevensek S, et al. Plant Cell, 2012 Jan. PMID 22286137 Free PMC Article Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor alpha are altered by the centrosome-associated protein CAP350. Patel H, et al. J Cell Sci, 2005 Jan 1. PMID 15615782

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CEP350 Polyclonal Antibody, 100μg, (ATB-T0860)
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