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CNOT2 Polyclonal Antibody, 100μg, (ATB-T1000)
Background: This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]Product datasheet: Overview Product Description CNOT2 Polyclonal Antibody, 100μg, (ATB-T1000) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human CNOT2 around the non-phosphorylation site of S101. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death. Ito K, et al. Genes Cells, 2011 Apr. PMID 21299754 Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex. Zwartjes CG, et al. J Biol Chem, 2004 Mar 19. PMID 14707134 The CCR4-NOT complex plays diverse roles in mRNA metabolism. Denis CL, et al. Prog Nucleic Acid Res Mol Biol, 2003. PMID 12882519 The cyclin-dependent kinase 11 interacts with NOT2. Shi J, et al. Biochem Biophys Res Commun, 2005 Sep 9. PMID 16039607 Structure and assembly of the NOT module of the human CCR4-NOT complex. Boland A, et al. Nat Struct Mol Biol, 2013 Nov. PMID 24121232
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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We ship our medical lab equipment to customers nationwide. Browse our online shop to view our impressive inventory of available lab equipment today and purchase the products that meet your unique style and needs. We can't wait to prove why Intelixbio.com is one of the nation's best medical lab supply providers.
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