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COMT Polyclonal Antibody, 100μg, (ATB-T1040)
Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]Product datasheet: Overview Product Description COMT Polyclonal Antibody, 100μg, (ATB-T1040) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human COMT. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: [Lack of association of COMT Val158Met polymorphism with attention and executive function in patients with schizophrenia]. Wang Q, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2014 Oct. PMID 25297602 Polymorphisms in catechol-O-methyltransferase modify treatment effects of aspirin on risk of cardiovascular disease. Hall KT, et al. Arterioscler Thromb Vasc Biol, 2014 Sep. PMID 25035343 Interactive effects of the COMT gene and training on individual differences in supervisory control of unmanned vehicles. Parasuraman R, et al. Hum Factors, 2014 Jun. PMID 25029900 Dissociable contribution of prefrontal and striatal dopaminergic genes to learning in economic games. Set E, et al. Proc Natl Acad Sci U S A, 2014 Jul 1. PMID 24979760 Free PMC Article A novel catechol-O-methyltransferase variant associated with human disc degeneration. Gruber HE, et al. Int J Med Sci, 2014. PMID 24904231 Free PMC Article
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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