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CROT Polyclonal Antibody, 100μg, (ATB-T1118)

$199.00
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Product Details

Background: This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]Product datasheet: Overview Product Description CROT Polyclonal Antibody, 100μg, (ATB-T1118) Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human CROT. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Changes in carnitine octanoyltransferase activity induce alteration in fatty acid metabolism. Le Borgne F, et al. Biochem Biophys Res Commun, 2011 Jun 17. PMID 21619872 In vitro selection of adenine-dependent ribozyme against Tpl2/Cot oncogene. Li YL, et al. FEBS J, 2009 Jan. PMID 19054068 Structural model of a malonyl-CoA-binding site of carnitine octanoyltransferase and carnitine palmitoyltransferase I: mutational analysis of a malonyl-CoA affinity domain. Morillas M, et al. J Biol Chem, 2002 Mar 29. PMID 11790793 Molecular cloning and expression of human carnitine octanoyltransferase: evidence for its role in the peroxisomal beta-oxidation of branched-chain fatty acids. Ferdinandusse S, et al. Biochem Biophys Res Commun, 1999 Sep 16. PMID 10486279 Genomics of the human carnitine acyltransferase genes. van der Leij FR, et al. Mol Genet Metab, 2000 Sep-Oct. PMID 11001805

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CROT Polyclonal Antibody, 100μg, (ATB-T1118)
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