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CRSP34 Polyclonal Antibody, 100μg, (ATB-T1122)
Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]Product datasheet: Overview Product Description CRSP34 Polyclonal Antibody, 100μg, (ATB-T1122) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the Internal region of human CRSP34. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: [Relation between manifest bronchial obstruction and bronchial hyperreactivity (author's transl)]. Roth J, et al. Z Erkr Atmungsorgane, 1976 Jul. PMID 1020353 The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. Ryu S, et al. Nature, 1999 Feb 4. PMID 9989412 Characterization of the influence of mediator complex in HIV-1 transcription. Ruiz A, et al. J Biol Chem, 2014 Oct 3. PMID 25100719 The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs. Malik S, et al. Mol Cell, 2000 Apr. PMID 10882111 A pancreatic cancer-specific expression profile. Gress TM, et al. Oncogene, 1996 Oct 17. PMID 8895530
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
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- Immunohistochemistry Tools
- Instruments and Equipment
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