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CTDSP1 Polyclonal Antibody, 100μg, (ATB-T1150)

$199.00
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Background: This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]Product datasheet: Overview Product Description CTDSP1 Polyclonal Antibody, 100μg, (ATB-T1150) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the N-terminal region of human CTDSP1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: A study of substrate specificity for a CTD phosphatase, SCP1, by proteomic screening of binding partners. Kim YJ, et al. Biochem Biophys Res Commun, 2014 May 30. PMID 24769477 Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. Zhang M, et al. ACS Chem Biol, 2011 May 20. PMID 21348431 Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Zhang M, et al. Protein Sci, 2010 May. PMID 20222012 Free PMC Article Ethnic divergence and linkage disequilibrium of novel SNPs in the human NLI-IF gene: evidence of human origin and lack of association with tuberculosis susceptibility. Ma X, et al. J Hum Genet, 2002. PMID 11950066 Suppression of BMP-Smad signaling axis-induced osteoblastic differentiation by small C-terminal domain phosphatase 1, a Smad phosphatase. Kokabu S, et al. Mol Endocrinol, 2011 Mar. PMID 21239611

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CTDSP1 Polyclonal Antibody, 100μg, (ATB-T1150)
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