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CaMKIIδ Polyclonal Antibody, 100μg, (ATB-T5063)

$199.00
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Product Details

Background: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]Product datasheet: Overview Product Description CaMKIIδ Polyclonal Antibody, 100μg, (ATB-T5063) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human CaMKIIδ. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium. Sossalla S, et al. Circ Res, 2010 Oct 29. PMID 20814023 Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right. Currie S. Front Biosci (Landmark Ed), 2009 Jun 1. PMID 19482609 Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart. Maier LS, et al. Cardiovasc Res, 2007 Mar 1. PMID 17157285 Downregulation of delta CaM kinase II in human tumor cells. Tombes RM, et al. Biochim Biophys Acta, 1999 Oct 13. PMID 10525155 Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium. Hoch B, et al. Circ Res, 1999 Apr 2. PMID 10189359

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CaMKIIδ Polyclonal Antibody, 100μg, (ATB-T5063)
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