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Calgizzarin Polyclonal Antibody, 100μg, (ATB-T0610)

$199.00
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Product Details

Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Calgizzarin Polyclonal Antibody, 100μg, (ATB-T0610) Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Calgizzarin. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: S100A11 overexpression contributes to the malignant phenotype of papillary thyroid carcinoma. Anania MC, et al. J Clin Endocrinol Metab, 2013 Oct. PMID 23928665 NMR structure note: the structure of human calcium-bound S100A11. Hung KW, et al. J Biomol NMR, 2012 Oct. PMID 22903637 Selective expression of S100A11 in lung cancer and its role in regulating proliferation of adenocarcinomas cells. Hao J, et al. Mol Cell Biochem, 2012 Jan. PMID 21861103 S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activation. Fan C, et al. Mol Cell Proteomics, 2011 Mar. PMID 21139050 Free PMC Article Ca2+-binding protein S100A11: a novel diagnostic marker for breast carcinoma. Liu XG, et al. Oncol Rep, 2010 May. PMID 20372844

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Calgizzarin Polyclonal Antibody, 100μg, (ATB-T0610)
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