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Casein Kinase Iδ Polyclonal Antibody, 100μg, (ATB-T0650)

$199.00
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Background: This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]Product datasheet: Overview Product Description Casein Kinase Iδ Polyclonal Antibody, 100μg, (ATB-T0650) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Casein Kinase Iδ. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Relationship between a point mutation S97C in CK1δ protein and its affect on ATP-binding affinity. Kumar A, et al. J Biomol Struct Dyn, 2014. PMID 23527964 Casein kinase I delta controls centrosome positioning during T cell activation. Zyss D, et al. J Cell Biol, 2011 Nov 28. PMID 22123863 Free PMC Article Disease-associated casein kinase I delta mutation may promote adenomatous polyps formation via a Wnt/beta-catenin independent mechanism. Tsai IC, et al. Int J Cancer, 2007 Mar 1. PMID 17131344 Inhibition of casein kinase I delta alters mitotic spindle formation and induces apoptosis in trophoblast cells. Stöter M, et al. Oncogene, 2005 Dec 1. PMID 16027726 Catalytic activity of protein kinase CK1 delta (casein kinase 1delta) is essential for its normal subcellular localization. Milne DM, et al. Exp Cell Res, 2001 Feb 1. PMID 11161704

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Casein Kinase Iδ Polyclonal Antibody, 100μg, (ATB-T0650)
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