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Catalase Polyclonal Antibody, 100μg, (ATB-T15155)

$199.00
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Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]Product datasheet: Overview Product Description Catalase Polyclonal Antibody, 100μg, (ATB-T15155) Image Species Reactivities Human Immunogen Synthesized peptide derived from the C-terminal region of human Catalase. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Association of the 389 C/T polymorphism of the catalase gene with susceptibility to vitiligo: a meta-analysis. Lu L, et al. Clin Exp Dermatol, 2014 Jun. PMID 24825136 Association of the CAT-262C>T polymorphism with asthma in smokers and the nonemphysematous phenotype of chronic obstructive pulmonary disease. Taniguchi N, et al. Ann Allergy Asthma Immunol, 2014 Jul. PMID 24824229 Clinical relevance of tag single nucleotide polymorphisms within the CAT gene in patients with PTSD in the Chongqing Han population. Duan ZX, et al. Int J Clin Exp Pathol, 2014. PMID 24817970 Free PMC Article Increased microglial catalase activity in multiple sclerosis grey matter. Gray E, et al. Brain Res, 2014 Apr 22. PMID 24602691 Analysis of catalase SNP rs1001179 in Saudi patients with primary open angle glaucoma. Abu-Amero KK, et al. Ophthalmic Genet, 2013 Dec. PMID 24215654

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Catalase Polyclonal Antibody, 100μg, (ATB-T15155)
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