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Catenin-γ Polyclonal Antibody, 100μg, (ATB-T0678)

$199.00
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Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Catenin-γ Polyclonal Antibody, 100μg, (ATB-T0678) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human Catenin-γ. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Plakoglobin but not desmoplakin regulates keratinocyte cohesion via modulation of p38MAPK signaling. Spindler V, et al. J Invest Dermatol, 2014 Jun. PMID 24441103 On the diagnostic utility of junction plakoglobin in arrhythmogenic right ventricular cardiomyopathy. Marian AJ. Cardiovasc Pathol, 2013 Sep-Oct. PMID 23806441 Reduced plakoglobin immunoreactivity in arrhythmogenic cardiomyopathy: methodological considerations. Noorman M, et al. Cardiovasc Pathol, 2013 Sep-Oct. PMID 23688911 Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis. Cooksley-Decasper S, et al. PLoS One, 2012. PMID 23110151 Free PMC Article The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling. Franzen CA, et al. PLoS One, 2012. PMID 22860065 Free PMC Article

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Catenin-γ Polyclonal Antibody, 100μg, (ATB-T0678)
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