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Cdc42EP4 Polyclonal Antibody, 100μg, (ATB-T0810)

$199.00
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Product Details

Background: The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Cdc42EP4 Polyclonal Antibody, 100μg, (ATB-T0810) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human Cdc42EP4. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Sequence analysis, gene expression, and chromosomal assignment of mouse Borg4 gene and its human orthologue. Osada N, et al. J Hum Genet, 2000. PMID 11185749 A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes. Hirsch DS, et al. J Biol Chem, 2001 Jan 12. PMID 11035016 The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. Joberty G, et al. Mol Cell Biol, 1999 Oct. PMID 10490598 Free PMC Article Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase. Guo Z, et al. J Proteome Res, 2012 Oct 5. PMID 22889411 VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. Yu CC, et al. PLoS One, 2013. PMID 23383273 Free PMC Article

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Cdc42EP4 Polyclonal Antibody, 100μg, (ATB-T0810)
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