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CyPB Polyclonal Antibody, 100μg, (ATB-T15436)

$199.00
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Product Details

Background: The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]Product datasheet: Overview Product Description CyPB Polyclonal Antibody, 100μg, (ATB-T15436) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human CyPB. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. Ray P, et al. J Clin Invest, 2012 May. PMID 22484812 Free PMC Article Spatiotemporal behavior of nuclear cyclophilin B indicates a role in RNA transcription. Dieriks B, et al. Int J Mol Med, 2012 Jun. PMID 22426501 Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans. Kim Y, et al. Hepatology, 2011 Nov. PMID 21748762 Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes. Pyott SM, et al. Hum Mol Genet, 2011 Apr 15. PMID 21282188 Free PMC Article Cyclophilin B as a co-regulator of prolactin-induced gene expression and function in breast cancer cells. Fang F, et al. J Mol Endocrinol, 2010 Jun. PMID 20237142 Free PMC Article

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CyPB Polyclonal Antibody, 100μg, (ATB-T15436)
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