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Cytokeratin 19 Polyclonal Antibody, 100μg, (ATB-T15349)

$199.00
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Background: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Cytokeratin 19 Polyclonal Antibody, 100μg, (ATB-T15349) Image Species Reactivities Human Immunogen Synthesized peptide derived from the C-terminal region of human Cytokeratin 19. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Improvement of the cytological diagnostic accuracy of follicular thyroid lesions by the use of the Ki-67 proliferative index in addition to cytokeratin-19 and HBME-1 immunomarkers: a study of 61 cases of liquid-based FNA cytology with histological controls. Lacoste-Collin L, et al. Cytopathology, 2014 Jun. PMID 24460983 Cytokeratin-19 as a biomarker in urine and in serum for the diagnosis of endometriosis--a prospective study. Kuessel L, et al. Gynecol Endocrinol, 2014 Jan. PMID 24219598 CK-19 mRNA-positive cells in peripheral blood predict treatment efficacy and survival in small-cell lung cancer patients. Shi WL, et al. Med Oncol, 2013 Dec. PMID 24178178 Keratin 19: a key role player in the invasion of human hepatocellular carcinomas. Govaere O, et al. Gut, 2014 Apr. PMID 23958557 Free PMC Article Clinicopathological significance of combined analysis of cytokeratin19 expression and preoperative serum CYFRA21-1 levels in human lung squamous cell carcinoma. Hanada S, et al. Osaka City Med J, 2013 Jun. PMID 23909079

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Cytokeratin 19 Polyclonal Antibody, 100μg, (ATB-T15349)
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