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DPP7 Polyclonal Antibody, 100μg, (ATB-T5125)

$199.00
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Product Details

Background: The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description DPP7 Polyclonal Antibody, 100μg, (ATB-T5125) Image Species Reactivities Human Immunogen Synthesized peptide derived from the C-terminal region of human DPP7. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases. Bezerra GA, et al. PLoS One, 2012. PMID 22952628 Free PMC Article Dipeptidyl peptidase 2 is an essential survival factor in the regulation of cell quiescence. Mele DA, et al. Cell Cycle, 2009 Aug. PMID 19556882 Dipeptidyl peptidase II is not a marker for progression in melanoma. Fröhlich E, et al. J Dermatol Sci, 2009 Jan. PMID 18823758 Peptidases play an important role in cataractogenesis: an immunohistochemical study on lenses derived from Shumiya cataract rats. Zhan H, et al. Histochem J, 2001 Sep-Oct. PMID 12005022 Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase. Chiravuri M, et al. J Immunol, 2000 Nov 15. PMID 11067927

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DPP7 Polyclonal Antibody, 100μg, (ATB-T5125)
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