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Duo Polyclonal Antibody, 100μg, (ATB-T1421)

$199.00
In stock
Product Details

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Duo Polyclonal Antibody, 100μg, (ATB-T1421) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Duo. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formation. Tsai YC, et al. PLoS One, 2012. PMID 23284848 Free PMC Article Genetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients. Tsai YC, et al. BMC Med Genet, 2012 Jun 21. PMID 22720673 Free PMC Article β-Amyloid 42/40 ratio and kalirin expression in Alzheimer disease with psychosis. Murray PS, et al. Neurobiol Aging, 2012 Dec. PMID 22429885 Free PMC Article Kalirin signaling: implications for synaptic pathology. Penzes P, et al. Mol Neurobiol, 2012 Feb. PMID 22194219 Free PMC Article Increased expression of Kalirin-9 in the auditory cortex of schizophrenia subjects: its role in dendritic pathology. Deo AJ, et al. Neurobiol Dis, 2012 Feb. PMID 22120753 Free PMC Article

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Duo Polyclonal Antibody, 100μg, (ATB-T1421)
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