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Dyrk4 Polyclonal Antibody, 100μg, (ATB-T1437)

$199.00
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Product Details

Background: This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013]Product datasheet: Overview Product Description Dyrk4 Polyclonal Antibody, 100μg, (ATB-T1437) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human Dyrk4. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity. Papadopoulos C, et al. J Biol Chem, 2011 Feb 18. PMID 21127067 Free PMC Article The expression of the testis-specific Dyrk4 kinase is highly restricted to step 8 spermatids but is not required for male fertility in mice. Sacher F, et al. Mol Cell Endocrinol, 2007 Mar 15. PMID 17292540 DYRK gene structure and erythroid-restricted features of DYRK3 gene expression. Zhang D, et al. Genomics, 2005 Jan. PMID 15607427 Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. Becker W, et al. J Biol Chem, 1998 Oct 2. PMID 9748265 Identification of the human testis protein phosphatase 1 interactome. Fardilha M, et al. Biochem Pharmacol, 2011 Nov 15. PMID 21382349

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Dyrk4 Polyclonal Antibody, 100μg, (ATB-T1437)
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