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E-Ras Polyclonal Antibody, 100μg, (ATB-T1607)

$199.00
In stock
Product Details

Background: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]Product datasheet: Overview Product Description E-Ras Polyclonal Antibody, 100μg, (ATB-T1607) Image Species Reactivities Human Immunogen Synthesized peptide derived from the C-terminal region of human E-Ras. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Role of the ERas gene in gastric cancer cells. Liu Y, et al. Oncol Rep, 2013 Jul. PMID 23612786 Free PMC Article ERas enhances resistance to CPT-11 in gastric cancer. Kubota E, et al. Anticancer Res, 2011 Oct. PMID 21965746 Identification of HLA-A*2402-restricted epitope peptide derived from ERas oncogene expressed in human scirrhous gastric cancer. Iwauchi T, et al. Cancer Sci, 2011 Apr. PMID 21205089 Resistance to chemotherapeutic agents and promotion of transforming activity mediated by embryonic stem cell-expressed Ras (ERas) signal in neuroblastoma cells. Aoyama M, et al. Int J Oncol, 2010 Oct. PMID 20811723 Role of ES cell-expressed Ras (ERas) in tumorigenicity of gastric cancer. Kubota E, et al. Am J Pathol, 2010 Aug. PMID 20566745 Free PMC Article

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E-Ras Polyclonal Antibody, 100μg, (ATB-T1607)
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