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EP3 Polyclonal Antibody, 100μg, (ATB-T1569)

$199.00
In stock
Product Details

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]Product datasheet: Overview Product Description EP3 Polyclonal Antibody, 100μg, (ATB-T1569) Image Species Reactivities Human Immunogen Synthesized peptide derived from the N-terminal region of human EP3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Neuronal prostaglandin E2 receptor subtype EP3 mediates antinociception during inflammation. Natura G, et al. Proc Natl Acad Sci U S A, 2013 Aug 13. PMID 23904482 Free PMC Article Association of a common genetic factor, PTGER3, with outcome of periodontal therapy and preterm birth. Jeffcoat MK, et al. J Periodontol, 2014 Mar. PMID 23805813 Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease. Shi J, et al. Ann Neurol, 2012 Nov. PMID 22915243 Free PMC Article Laropiprant attenuates EP3 and TP prostanoid receptor-mediated thrombus formation. Philipose S, et al. PLoS One, 2012. PMID 22870195 Free PMC Article Prostaglandin E₂ induced contraction of human intercostal arteries is mediated by the EP₃ receptor. Longrois D, et al. Eur J Pharmacol, 2012 Apr 15. PMID 22342278

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EP3 Polyclonal Antibody, 100μg, (ATB-T1569)
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