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ETAR Polyclonal Antibody, 100μg, (ATB-T1639)

$199.00
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Background: This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]Product datasheet: Overview Product Description ETAR Polyclonal Antibody, 100μg, (ATB-T1639) Image Species Reactivities Human,Mouse,Monkey Immunogen Synthesized peptide derived from the C-terminal region of human ETAR. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Polymorphisms of endothelin 1 (G5665T and T-1370G) and endothelin receptor type A (C+70G and G-231A) in Graves' disease. Aydın AF, et al. Int Immunopharmacol, 2014 Jan. PMID 24291390 Role of endothelin A receptor in colon cancer metastasis: in vitro and in vivo evidence. Nie S, et al. Mol Carcinog, 2014 Feb. PMID 23818293 Whole exome sequencing identifies mutation of EDNRA involved in ACTH-independent macronodular adrenal hyperplasia. Zhu J, et al. Fam Cancer, 2013 Dec. PMID 23754170 Association of 231G>A polymorphism of endothelin type A receptor gene with migraine: a meta-analysis. Miao J, et al. J Neurol Sci, 2012 Dec 15. PMID 23058564 Purification and characterization of recombinant human endothelin receptor type A. Lee K, et al. Protein Expr Purif, 2012 Jul. PMID 22561246

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ETAR Polyclonal Antibody, 100μg, (ATB-T1639)
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