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Eotaxin-3 Polyclonal Antibody, 100μg, (ATB-T15150)

$199.00
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Product Details

Background: This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Eotaxin-3 Polyclonal Antibody, 100μg, (ATB-T15150) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human Eotaxin-3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Demethylation of the human eotaxin-3 gene promoter leads to the elevated expression of eotaxin-3. Lim E, et al. J Immunol, 2014 Jan 1. PMID 24323578 Free PMC Article Regulation of eotaxin-3/CC chemokine ligand 26 expression by T helper type 2 cytokines in human colonic myofibroblasts. Takahashi K, et al. Clin Exp Immunol, 2013 Aug. PMID 23607908 Free PMC Article Omeprazole blocks eotaxin-3 expression by oesophageal squamous cells from patients with eosinophilic oesophagitis and GORD. Cheng E, et al. Gut, 2013 Jun. PMID 22580413 Free PMC Article Up-regulation of CCL11 and CCL26 is associated with activated eosinophils in bullous pemphigoid. Günther C, et al. Clin Exp Immunol, 2011 Nov. PMID 21985360 Free PMC Article High levels of CCL26 in blister fluid and sera of patients with bullous pemphigoid. Kagami S, et al. J Invest Dermatol, 2012 Jan. PMID 21881593

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Eotaxin-3 Polyclonal Antibody, 100μg, (ATB-T15150)
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