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EphA3 Polyclonal Antibody, 100μg, (ATB-T1577)
Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description EphA3 Polyclonal Antibody, 100μg, (ATB-T1577) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human EphA3 around the non-phosphorylation site of Y602. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Genome-wide copy number variation in sporadic amyotrophic lateral sclerosis in the Turkish population: deletion of EPHA3 is a possible protective factor. Uyan Ö, et al. PLoS One, 2013. PMID 23991104 Free PMC Article High levels of EphA3 expression are associated with high invasive capacity and poor overall survival in hepatocellular carcinoma. Lu CY, et al. Oncol Rep, 2013 Nov. PMID 23970317 EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme. Day BW, et al. Cancer Cell, 2013 Feb 11. PMID 23410976 A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Lahtela J, et al. Cell Cycle, 2013 Feb 15. PMID 23324396 Free PMC Article Effects of cancer-associated EPHA3 mutations on lung cancer. Zhuang G, et al. J Natl Cancer Inst, 2012 Aug 8. PMID 22829656 Free PMC Article
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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When you contact our team, you can expect fast, friendly, and professional assistance with all your medical lab equipment needs.