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Ephrin-A3 Polyclonal Antibody, 100μg, (ATB-T1591)

$199.00
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Background: This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Ephrin-A3 Polyclonal Antibody, 100μg, (ATB-T1591) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human Ephrin-A3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. Fasanaro P, et al. J Biol Chem, 2008 Jun 6. PMID 18417479 Free PMC Article Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3. Day B, et al. J Biol Chem, 2005 Jul 15. PMID 15901737 Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin. de Saint-Vis B, et al. Blood, 2003 Dec 15. PMID 12907451 A role for the Eph ligand ephrin-A3 in entorhino-hippocampal axon targeting. Stein E, et al. J Neurosci, 1999 Oct 15. PMID 10516308 Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10. Janes PW, et al. PLoS Biol, 2009 Oct. PMID 19823572 Free PMC Article

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Ephrin-A3 Polyclonal Antibody, 100μg, (ATB-T1591)
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