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Ezrin Polyclonal Antibody, 100μg, (ATB-T1650)

$199.00
In stock
Product Details

Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Ezrin Polyclonal Antibody, 100μg, (ATB-T1650) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human Ezrin around the non-phosphorylation site of Y478. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Role of ezrin in osteosarcoma metastasis. Ren L, et al. Adv Exp Med Biol, 2014. PMID 24924175 Reduced expression of ezrin in urothelial bladder cancer signifies more advanced tumours and an impaired survival: validatory study of two independent patient cohorts. Andersson G, et al. BMC Urol, 2014 May 12. PMID 24885195 Free PMC Article Prognostic implications of ezrin and phosphorylated ezrin expression in non-small cell lung cancer. Jin T, et al. BMC Cancer, 2014 Mar 15. PMID 24629131 Free PMC Article Correlation of the Rac1/RhoA pathway with ezrin expression in osteosarcoma. Chiappetta C, et al. Appl Immunohistochem Mol Morphol, 2014 Mar. PMID 24614149 Increased phosphorylation of ezrin is associated with the migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Xiao Y, et al. Rheumatology (Oxford), 2014 Jul. PMID 24599913

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Ezrin Polyclonal Antibody, 100μg, (ATB-T1650)
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