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FAF1 Polyclonal Antibody, 100μg, (ATB-T15149)

$199.00
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Product Details

Background: Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description FAF1 Polyclonal Antibody, 100μg, (ATB-T15149) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human FAF1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Crystal structure of human FAF1 UBX domain reveals a novel FcisP touch-turn motif in p97/VCP-binding region. Kang W, et al. Biochem Biophys Res Commun, 2011 Apr 15. PMID 21414298 Crystallization and preliminary X-ray crystallographic analysis of human FAF1 UBX domain. Kang W, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2010 Feb 1. PMID 20124726 Free PMC Article Structure and interaction of ubiquitin-associated domain of human Fas-associated factor 1. Song J, et al. Protein Sci, 2009 Nov. PMID 19722279 Free PMC Article Fas-associated factor 1 and Parkinson's disease. Betarbet R, et al. Neurobiol Dis, 2008 Sep. PMID 18573343 Free PMC Article The pro-apoptotic FAS-associated factor 1 is specifically reduced in human gastric carcinomas. Bjørling-Poulsen M, et al. Int J Oncol, 2003 Oct. PMID 12963981

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FAF1 Polyclonal Antibody, 100μg, (ATB-T15149)
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