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FGF-13 Polyclonal Antibody, 100μg, (ATB-T1696)

$199.00
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Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]Product datasheet: Overview Product Description FGF-13 Polyclonal Antibody, 100μg, (ATB-T1696) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human FGF-13. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Upregulated expression of FGF13/FHF2 mediates resistance to platinum drugs in cervical cancer cells. Okada T, et al. Sci Rep, 2013 Oct 11. PMID 24113164 Free PMC Article Xq26.3 microdeletion in a male with Wildervanck Syndrome. Abu-Amero KK, et al. Ophthalmic Genet, 2014 Mar. PMID 23373430 Identification of a novel domain of fibroblast growth factor 2 controlling its angiogenic properties. Facchiano A, et al. J Biol Chem, 2003 Mar 7. PMID 12496262 Fibroblast growth factor homologous factor 2 (FHF2): gene structure, expression and mapping to the Börjeson-Forssman-Lehmann syndrome region in Xq26 delineated by a duplication breakpoint in a BFLS-like patient. Gecz J, et al. Hum Genet, 1999 Jan. PMID 10071193 Pretreatment with intravenous FGF-13 reduces infarct volume and ameliorates neurological deficits following focal cerebral ischemia in rats. Yao DL, et al. Brain Res, 1999 Feb 6. PMID 9914447

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FGF-13 Polyclonal Antibody, 100μg, (ATB-T1696)
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