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FGF-18 Polyclonal Antibody, 100μg, (ATB-T15181)

$199.00
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Product Details

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description FGF-18 Polyclonal Antibody, 100μg, (ATB-T15181) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human FGF-18. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The crystal structure of fibroblast growth factor 18 (FGF18). Brown A, et al. Protein Cell, 2014 May. PMID 24668462 Free PMC Article Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling. Mori Y, et al. J Biol Chem, 2014 Apr 4. PMID 24577103 FGF18 as a prognostic and therapeutic biomarker in ovarian cancer. Wei W, et al. J Clin Invest, 2013 Oct. PMID 24018557 Free PMC Article Involvement of fibroblast growth factor 18 in dedifferentiation of cultured human chondrocytes. Yamaoka H, et al. Cell Prolif, 2010 Feb. PMID 19909293 FGF18 in colorectal tumour cells: autocrine and paracrine effects. Sonvilla G, et al. Carcinogenesis, 2008 Jan. PMID 17890768

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FGF-18 Polyclonal Antibody, 100μg, (ATB-T15181)
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