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FGF-9 Polyclonal Antibody, 100μg, (ATB-T15179)

$199.00
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Product Details

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description FGF-9 Polyclonal Antibody, 100μg, (ATB-T15179) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human FGF-9. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Chen TM, et al. Nucleic Acids Res, 2014 Mar. PMID 24334956 Free PMC Article Expression of fibroblast growth factor 9 is associated with poor prognosis in patients with resected non-small cell lung cancer. Ohgino K, et al. Lung Cancer, 2014 Jan. PMID 24239165 Association of aberrant expression of sex-determining gene fibroblast growth factor 9 with Sertoli cell-only syndrome. Chung CL, et al. Fertil Steril, 2013 Dec. PMID 24011613 Expression of fibroblast growth factor 9 in normal human lung and idiopathic pulmonary fibrosis. Coffey E, et al. J Histochem Cytochem, 2013 Sep. PMID 23797050 Free PMC Article Autoinhibitory mechanism for the mutation-induced impaired FGF9 signaling. Wang Y, et al. J Chem Inf Model, 2012 Sep 24. PMID 22920789

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FGF-9 Polyclonal Antibody, 100μg, (ATB-T15179)
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