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Fhit Polyclonal Antibody, 100μg, (ATB-T1705)
Background: This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]Product datasheet: Overview Product Description Fhit Polyclonal Antibody, 100μg, (ATB-T1705) Species Reactivities Human Immunogen Synthesized peptide derived from human Fhit around the non-phosphorylation site of Y114. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The FHIT gene product: tumor suppressor and genome "caretaker". Waters CE, et al. Cell Mol Life Sci, 2014 Dec. PMID 25283145 Fragile histidine triad (FHIT) suppresses proliferation and promotes apoptosis in cholangiocarcinoma cells by blocking PI3K-Akt pathway. Huang Q, et al. ScientificWorldJournal, 2014. PMID 24757411 Free PMC Article Abnormal FHIT protein expression may be correlated with poor prognosis in gastric cancer: a meta-analysis. Wang HL, et al. Tumour Biol, 2014 Jul. PMID 24729090 [The relationship between FHIT gene promoter methylation and lung cancer risk: a meta-analysis]. Sun Y. Zhongguo Fei Ai Za Zhi, 2014 Mar. PMID 24667261 Reduced FHIT expression is associated with tumor progression in sporadic colon adenocarcinoma. Kapitanović S, et al. Exp Mol Pathol, 2014 Feb. PMID 24370550
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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