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Fusin Polyclonal Antibody, 100μg, (ATB-T1800)

$199.00
In stock
Product Details

Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Fusin Polyclonal Antibody, 100μg, (ATB-T1800) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human Fusin. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Nuclear expression of chemokine receptor CXCR4 indicates poorer prognosis in gastric cancer. Masuda T, et al. Anticancer Res, 2014 Nov. PMID 25368239 Risk of breast cancer with CXCR4-using HIV defined by V3 loop sequencing. Goedert JJ, et al. J Acquir Immune Defic Syndr, 2015 Jan 1. PMID 25321183 The two human CXCR4 isoforms display different HIV receptor activities: consequences for the emergence of X4 strains. Duquenne C, et al. J Immunol, 2014 Oct 15. PMID 25230750 CXCR4 antagonist inhibits perineural invasion of adenoid cystic carcinoma. Jeong WJ, et al. J Clin Pathol, 2014 Nov. PMID 25118295 Intracellular trafficking and endocytosis of CXCR4 in fetal mesenchymal stem/stromal cells. Pelekanos RA, et al. BMC Cell Biol, 2014 May 16. PMID 24885150 Free PMC Article

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Fusin Polyclonal Antibody, 100μg, (ATB-T1800)
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