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GABA T-3 Polyclonal Antibody, 100μg, (ATB-T1820)

$199.00
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Product Details

Background: Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11 (Borden et al., 1994 [PubMed 7874447]).[supplied by OMIM, Nov 2010]Product datasheet: Overview Product Description GABA T-3 Polyclonal Antibody, 100μg, (ATB-T1820) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human GABA T-3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Gaba transporter SLC6A11 gene polymorphism associated with tardive dyskinesia. Son WY, et al. Nord J Psychiatry, 2014 Feb. PMID 23795861 Development and validation of an LC-ESI-MS/MS quantification method for a potential γ-aminobutyric acid transporter 3 (GAT3) marker and its application in preliminary MS binding assays. Polley M, et al. Biomed Chromatogr, 2013 May. PMID 23225341 Association of a synonymous GAT3 polymorphism with antiepileptic drug pharmacoresistance. Kim DU, et al. J Hum Genet, 2011 Sep. PMID 21776001 Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site. Borden LA, et al. Receptors Channels, 1994. PMID 7874447 Substrate-Na+ complex formation: coupling mechanism for gamma-aminobutyrate symporters. Palló A, et al. Biochem Biophys Res Commun, 2009 Jul 24. PMID 19450549

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GABA T-3 Polyclonal Antibody, 100μg, (ATB-T1820)
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